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Gibco™ LIF Recombinant Human Protein DFS Item

Recombinant human leukemia inhibitory factor (LIF) is a bioactive protein intended for use in cell culture applications

Manufacturer: gibco™  LSPHC9483

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For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Catalog No. PHC9483

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Description & Specifications


Molecular Weight 21kDa
Protein Tag Untagged
Source Human
Purification Method Sequential Chromatography
Storage Requirements Lyophilized form should be stored at 2° to 8°C, preferably desiccated. Reconstituted form should be stored at ≤ -20°C. Avoid freeze/thaw cycles.
For Use With (Application) Cell Culture; Mammalian Cell Culture
Biological Activity 0.5ng/mL
Purity 95%
Structural Form Recombinant/Ligand
Common Name Leukemia inhibitory factor
Protein Subtype Other Cytokines
Assays Dose-dependent proliferation of TF-1 cells
Gene Alias LIF
Gene Symbol LIF
Protein Family Cytokines & Receptors
Expression System E. coli
Quantity 1000μg

LIF is a cytokine that induces macrophage differentiation. LIF, in conjunction with BMP2, acts on primary fetal neural progenitor cells to induce astrocytes.

  • High purity: minimizes interference from other proteins or contaminants
  • High biological activity: more results with less protein
  • Proven compatibility: Gibco proteins bioassayed with Gibco media
  • High Purity Recombinant Bioactive Protein: to help ensure Gibco growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein
  • High Biological Activity: in-house activity testing of Gibco recombinant proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, anti-viral, and protease assays; specific activity is determined by measuring the LIF dose-dependent proliferation of Human TF-1 cells

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