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Gibco™ IL33 Recombinant Mouse Protein DFS Item


Recombinant IL33 is a bioactive protein intended for use in cell culture applications

Manufacturer: gibco™  LSPMC4043

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. PMC4043

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Description & Specifications

Specifications

Source Mouse
Cross Reactivity Mouse
Gene Alias IL-33
Format Lyophilized
Without Additives Carrier Protein
For Use With (Application) Cell Culture; Mammalian Cell Culture
Quantity 1mg
Structural Form Recombinant/Ligand
Molecular Weight 18kDa
Specific Reactivity 1.0 x 108 - 1.0 x 107 units/mg
Expression System E. coli
Endotoxin Concentration <0.1ng/μg
Gene ID (Entrez) IL33
Cell Type T Cells
Purification Method PAGE
Purity 95%
Validated Application Cell Culture
Protein Family Cytokines & Receptors
Storage Requirements Lyophilized Mouse IL-33 should be stored at 2° to 8°C, preferably desiccated. Store reconstituted Mouse IL-33 at ≤ –20°C. Avoid repeated freeze/thaw cycles.
Protein Length 267 aa
Accession Number NM_006853
Protein Subtype Interleukins

IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NFκB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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