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Gibco™ IL33 Recombinant Human Protein DFS Item


Recombinant IL33 is a bioactive protein intended for use in cell culture applications

Manufacturer: gibco™  LSPHC9254

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. PHC9254

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Description & Specifications

Specifications

Cross Reactivity Human
Storage Requirements Lyophilized Human IL-33 should be stored at 2° to 8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ -20°C. Avoid freeze/thaw cycles.
Without Additives Carrier Protein
Validated Application Cell Culture
Gene Alias IL-33
Purity 95%
Specific Reactivity 1.0 x 107 - 1.0 x 106 units/mg
Source Human
Gene ID (Entrez) 90865
Gene Symbol IL33
For Use With (Application) Cell Culture; Mammalian Cell Culture
Accession Number NM_033439
Protein Subtype Interleukins
Biological Activity ED50 range: 0.1 to 1.0ng/mL
Molecular Weight 18kDa
Assays Proliferation of Mouse D10S Cells
Purification Method Sequential Chromatography
Expression System E. coli
Structural Form Recombinant/Ligand
Protein Family Cytokines & Receptors
Format Lyophilized
Quantity 10μg
Endotoxin Concentration <0.1ng/μg
Protein Length 159 aa

IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NFκB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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