Collagenase is unique among proteases in its ability to degrade the triple-helical native collagen fibrils commonly found in connective tissues such as skin, tendon, blood vessels, and bone. Collagenase disaggregation is suitable for the culture of human tumors, mouse kidney, human adult and fetal brain, and many other tissues including epithelium. Collagenase is relatively gentle, dissociates well at physiological temperature and pH, and requires no mechanical agitation or special equipment.
- Isolated from Clostridium histolyticum.
- Packaged as lyophilized, non-sterile powder for research use in cell or tissue dissociation, and organ perfusions
- Activity is >125 units/mg
- Contains average levels of collagenase, caseinase, clostripain, and tryptic activities, and is well-suited for digestion of fat, adrenal, and liver cells or tissues
Cell Culture, Mammalian Cell Culture
Shipping Condition: Room Temperature
|Storage: 2°C to 8°C. Protect from light. Shelf life: 24 months from date of manufacture|