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Gibco™ BMP2 Recombinant Human Protein DFS Item


Recombinant Human Bone Morphogenetic Protein 2 (BMP2) is a bioactive protein intended for use in cell culture applications

Manufacturer: gibco™  LSPHC7146

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 Disclaimers

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Catalog No. PHC7146

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Description & Specifications

Specifications

Source Human
Structural Form Recombinant/Ligand
Gene ID (Entrez) 548717
Storage Requirements Store lyophilized human BMP-2 at 2° to 8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ -20°C. Avoid repeated freeze/thaw cycles.
Expression System E. coli
Protein Family Growth Factors & Receptors
Quantity 25μg
Purification Method Sequential Chromatography
Endotoxin Concentration <0.1ng/μg
Cross Reactivity Human
Gene Alias BMP-2, BMP-2, mgC114605, xBMP-2, xbmp2
Validated Application Cell Culture
For Use With (Application) Cell Culture; Mammalian Cell Culture; Cell Analysis; Cell Viability, Proliferation & Function; Cell Proliferation
Format Lyophilized
Protein Subtype BMPs (Bone Morphogenetic Proteins) & Related Factors
Accession Number NM001200
Purity 95%
Without Additives Carrier Protein
Specific Reactivity 1.0 x 104 - 1.0 x103 units/mg
Cell Type Stem Cells
Biological Activity ED50 range = 0.1-1.0mg/mL
Molecular Weight 26kDa

BMP2 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.

  • High purity: no interference from other proteins or contaminants
  • High biological activity: more results with less protein
  • Proven compatibility: Gibco proteins bioassayed with Gibco media
  • High Purity Recombinant Bioactive Protein: to help ensure Gibco growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein
  • High Biological Activity: in-house activity testing of Gibco Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, anti-viral, and protease assays; specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5
  • Proven Compatibility: Gibco proteins are bioassayed with Gibco media

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