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GE Healthcare Sepharose™ Fast Flow Cation Exchange Media

Used for preparative protein separations in both research and industrial applications. GE Healthcare CM Sepharose™ Fast Flow Cation Exchange Media is composed of crosslinked 6% agarose beads, with carboxymethyl (CM) weak cation exchange groups.

$87.33 - $669.00


Particle Size 45 to 165μm
pH Range 4 to 13
View More Specs
Catalog Number Mfr. No. Binding Capacity Packaging Quantity Product Type Price Quantity    


ge healthcare
50mg Ribonuclease A/mL medium 500mL CM Sepharose fast flow media Each for $669.00


ge healthcare
70mg Ribonuclease A/mL medium 300mL SP Sepharose fast flow media Each for $547.00


ge healthcare
50mg ribonuclease A/mL medium 25mL CM Sepharose Fast Flow Each for $87.33


ge healthcare
70mg Ribonuclease A/mL medium 25mL SP Sepharose fast flow media Each for $87.33
Description & Specifications


Particle Size 45 to 165μm
pH Range 4 to 13

  • Hydrophilic nature of base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool
  • Composed of crosslinked 6% agarose beads
  • Reproducible
  • Part of Sepharose Fast Flow ion exchange platform
  • High chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols
  • Available in range of pre-packed process development tools

SP Sepharose:

  • Ligand: Sulphopropyl
  • Ion Exchanger Type: Strong cation exchanger
  • Ionic Capacity: 0.18 to 0.25mmol H+/mL medium
  • Binding capacity: 70mg ribonuclease A/mL medium
CM Sepharose:
  • Ligand: Carboxymethyl
  • Ion Exchanger Type: Weak cation exchanger
  • Ionic Capacity: 0.09 to 0.13mmol Hl+/mL medium
  • Binding capacity: 50mg ribonuclease A/mL medium

Used extensively for capture and intermediate purification of wide range of approved biopharmaceuticals