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Cytiva MabSelect™ Chromatography Media
Protein A affinity medium designed for capturing MAbs from large sample volumes
Supplier: Cytiva 17519901
Description
- High-flow agarose matrix allows for high flow velocities at production scale
- BioProcess medium supported for industrial applications and well-established in approved processes
- Low non-specific binding resulting in low levels of impurities in the product eluate pool
- Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity
- Based on highly cross-linked agarose matrix with recombinant protein A ligand
- Ligand is engineered to favor oriented coupling and expressed in E. coli and is free of components of mammalian origin
- Hydrophilic nature of the base matrix ensures low levels of non-specific
- Average particle size: 85μm (d50V)
- pH Stability cleaning-in-place (CIP): 2 to 12
- pH Stability working range: 3 to 10
- Ligand: recombinant protein A (E.coli)
- Matrix: highly cross-linked agarose
- Binding capacity/mL chromatography medium: ∽30mg human lgG/mL at 2.4 min. residence time
- Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm
Specifications
| 25 mL | |
| 2°C to 8°C | |
| MabSelect Media | |
| 85 μm | |
| 20 cm | |
| <200 kPa | |
| 3 to 10 |
| For Industrial AppliCatIons and Well-Established in Approved Processes | |
| 30 mg Human lgG/mL (at 2.4 min. residence time) | |
| <500 cm/Hoμr | |
| 7.87 in. | |
| Certificate of Analysis | |
| Highly Cross-Linked Agarose | |
| Recombinant Protein A (E. coli) |