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GE Healthcare HiTrap™ MabSelect™ Prepacked Columns

Use these columns in small-scale MAb purification in a continuous bioprocess. GE Healthcare Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes

$801.00 - $3,238.00

Specifications

Storage Requirements 4° to 30°C
Storage Buffer 20% Ethanol
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Diameter (Metric) Inner Column Binding Capacity Flow Rate Quantity Price Quantity  
Catalog Number Mfr. No. Diameter (Metric) Inner Column Binding Capacity Flow Rate Quantity Price Quantity  
45-001-463 GE Healthcare
28408255
1.6cm ≈30mg Human lgG/mL at 2.4 min. residence time <20mL/min. Each Each for $801.00
45-001-465 GE Healthcare
28408258
0.7cm ≈40mg Human lgG/mL at 2.4 min. residence time <4mL/min. 5 Pack Pack of 5 Each for $833.00
45-001-467 GE Healthcare
28408261
1.6cm ≈40mg Human lgG/mL at 2.4 min. residence time <4mL/min. 5 Pack Pack of 5 Each for $3,238.00
45-001-464 GE Healthcare
28408256
1.6cm ≈30mg Human lgG/mL at 2.4 min. residence time <20mL/min. 5 Pack Pack of 5 Each for $3,238.00
45-001-462 GE Healthcare
28408253
0.7cm ≈30mg Human lgG/mL at 2.4 min. residence time <4mL/min. 5 Pack Pack of 5 Each for $833.00
Specifications

Description

Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.

  • Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
  • High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
  • Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
  • Designed for use with a syringe, a peristaltic pump, or a chromatography system

MabSelect

  • Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
  • Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
MabSelect Xtra™
  • Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
  • Allows binding from samples with high expression levels of the monoclonal antibody
  • Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
MabSelect SuRe™ (Superior Resistance)
  • Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
  • Permits significant cost savings and extension of cycles in regular production

Description & Specifications

Specifications

4° to 30°C
20% Ethanol