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GE Healthcare Dharmacon siGENOME™ Non-Targeting siRNA Pools

Manufacturer: ge healthcare dharmacon  D-001206-14-05

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Catalog No. D0012061405


Description & Specifications


For Use With (Application) Determination of baseline cellular responses in RNAi experiments
Quantity 5nm

  • BLAST analysis confirms at least 4 mismatches with all known human, mouse and rat genes
  • Characterized by microarray analysis
  • Minimal off-target effects

The siGENOME Non-Targeting Pools are each comprised of four siGENOME Non-Targeting siRNAs, and are recommended for experiments using pooled siRNA such as Dharmacon SMARTpool reagents. Each individual siRNA within this pool was characterized by genome-wide microarray analysis and found to have minimal off-target signatures.
siGENOME Non-Targeting Pool #1 is comprised of Non-Targeting siRNAs #1-4

siGENOME Non-Targeting Pool #2 is comprised of Non-Targeting siRNAs #2-5

Please Note: Customer reports have shown that siGENOME Non-targeting siRNA #1 reduces EGFR mRNA (NM_005228) in an assay- and cell-specific manner by ∽50%. This finding was not observed by initial microarray validation, but has been subsequently verified by internal scientists.

siGENOME Non-Targeting siRNA #2 and #4 target firefly luciferase (U47296).