We offer two universal negative controls for both inhibitors and mimics that are based on the sequences of two miRNAs in C. elegans.
These miRNAs have been confirmed to have minimal sequence identity with miRNAs in human, mouse and rat. We recommend using the mature sequence information to determine which control would be most appropriate for the miRNA being studied.
Negative control sequence based on cel-miR-67, mature sequence: UCACAACCUCCUAGAAAGAGUAGA and Accession Number: MIMAT0000039
Cel-miR-67 has been confirmed to have minimal sequence identity with miRNAs in human, mouse and rat