missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Gata-3 Rat anti-Human, Mouse, PE-eFluor 610, Clone: TWAJ, eBioscience™

Rat Monoclonal Antibody

$183.48 - $460.68

Specifications

Antigen Gata-3
Clone TWAJ
Host Species Rat
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124894 Life Technologies
LS61996641
25 Tests Each for $183.48
501124895 Life Technologies
LS61996642
100 Tests Each for $460.68
Specifications

Description

The monoclonal antibody TWAJ recognizes mouse and human Gata-3, a member of the Gata family of transcription factors. Gata-3 is a T cell-specific transcription factor important for thymic development and Th2 differentiation. Expression during embryonic development is found in the central nervous system, skin, mammary glands and kidney. During development, the expression of Gata-3 is essential as homozygous knock-out of Gata-3 is embryonic lethal. The Gata-3 is also essential for T cell commitment and survival. In the thymus, expression is found mainly on the CD4 single positive cells. During Th2 differentiation, Gata-3 binds to the IL-4 promoter as well as represses the expression of T-bet, thus inhibiting Th1 differentiation.

Alternative splice variants have been reported especially in the MCF7 cell line. The TWAJ Human/Mouse Gata-3 antibody will recognize both forms (50 and 45 kDa) of the protein.

Staining with the TWAJ Human/Mouse Gata-3 antibody requires the use of the Foxp3/Transcription Factor Staining Buffer Set.
Description & Specifications

Specifications

Gata-3
Rat
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TWAJ
Flow Cytometry (Intracellular Staining)
PE-eFluor 610
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.03μg)/test