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GARP Rat anti-Mouse, eFluor 450, Clone: YGIC86, eBioscience™

Rat Monoclonal Antibody

$201.55 - $506.05

Specifications

Antigen GARP
Clone YGIC86
Host Species Rat
Gene Alias Lrrc32, Garpin
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124236

 
affymetrix
48989182
100μg Each for $506.05

5016415

 
affymetrix
48-9891-80
25μg Each for $201.55
Description & Specifications

Specifications

Antigen GARP
Clone YGIC86
Host Species Rat
Gene Alias Lrrc32, Garpin
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The YGIC86 monoclonal antibody reacts with mouse Glycoprotein A Repetitions Predominant (GARP, also known as Lrrc32 or Garpin). GARP is an approximately 80kDa glycoprotein that is expressed on the cell surface. Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas. Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells. The expression of GARP on Treg cells has been reported to be necessary for the suppressive function of Treg cells, possibly related to its role as a cell surface receptor for LAP/TGF beta.

When looking for expression of GARP on platelets, it is recommended to use the Foxp3 Staining Buffer Set (cat. 00-5523) to fix the platelets before staining with this YGIC86 monoclonal antibody. Fixation/permeabilization is not necessary when staining Treg cells.

YGIC86 does not cross-react to rat GARP.