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Fumonisin B1, 96%, Thermo Scientific™
Fumonisin, CAS # 116355-83-0, also known as Macrofusine, is a cell permeable mycotoxin that is an inhibitor of sphingosine N-acetyl transferase.
Supplier: Thermo Scientific Chemicals 328250050
Description
This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Fumonisin is a fungal metabolite that is a cell permeable mycotoxin that can halt sphingolipid biosynthesis by inhibiting sphingosine N-acetyl transferase
Applications
• It can potently inhibit sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases
• It is also a protein serine and threonine phosphatase inhibitor
• It can selectively inhibit sphingomyelin biosynthesis in neuronal cells
Specifications
| Fumonisin B1 | |
| 55.00 to 58.00%C, 1.60 to 2.20%N | |
| C34H59NO15 | |
| 5mg | |
| macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| UVBUBMSSQKOIBE-UWCNXKJPSA-N | |
| (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid | |
| 16760030 | |
| 96% |
| 116355-83-0 | |
| 95% min. (HPLC) | |
| MFCD00133349 | |
| 15, 4318 | |
| Solubility in water: soluble. Other solubilities: soluble in methanol,acetonitrile | |
| CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O | |
| 721.8 | |
| 721.8 |
Chemical Identifiers
| 116355-83-0 | |
| 721.8 | |
| UVBUBMSSQKOIBE-UWCNXKJPSA-N | |
| 16760030 | |
| CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O |
| C34H59NO15 | |
| MFCD00133349 | |
| macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
Safety and Handling
GHS H Statement:
Suspected of causing cancer.
GHS P Statement:
Use personal protective equipment as required.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
RUO â Research Use Only