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FR4 Rat anti-Mouse, Clone: eBioTH6, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$477.05 - $592.68

Specifications

Antigen FR4
Clone eBioTH6
Host Species Rat
Gene Alias Folate receptor 4, FOLR4 FRdelta, FRd
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014563 Life Technologies
LS16544682
100μg Each for $477.05
5014564 Life Technologies
LS16544685
500μg Each for $592.68
Specifications

Description

The monoclonal antibody eBioTh6 recognizes FR4, also known as FR δ and FBP3 (folate binding protein3). FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naïve T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.

Based on co-staining studies, the epitopes recognized by eBioTH6 and eBio12A5 (cat 51-5445) are different thereby allowing functional studies with TH6 to be evaluated with eBio12A5.
Description & Specifications

Specifications

FR4
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, no sodium azide
eBioTH6
Folate receptor 4, FOLR4 FRdelta, FRd
Flow Cytometry,Functional Assay,Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL