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Tocris™ FR 180204

Selective ERK inhibitor

$323.02 - $1,336.15

Specifications

Product Type FR 180204
Inhibitors FR 180204
Molecular Weight 327.34
Purity >98
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
370610R Tocris™
370610
10mg Each for $323.02
370650R Tocris™
370650
50mg Each for $1,336.15
Specifications

Description

Selective ERK inhibitor (IC50 values are 0.14 and 0.31μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1μM).
  • Chemical Name: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
  • Formula: C18H13N7
  • CAS Number: 865362-74-9
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

FR 180204
FR 180204
327.34
>98