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Foxp3 Mouse anti-Human, FITC, Clone: 236A/E7, eBioscience™

Mouse Monoclonal Antibody

$174.24 - $361.68

Specifications

Antigen Foxp3
Clone 236A/E7
Host Species Murine
Gene Alias Forkhead Box P3, Scurfin, JM2
Applications Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122126 Life Technologies
LS11477741
25 Tests Each for $174.24
501122127 Life Technologies
LS11477742
100 Tests Each for $361.68
Specifications

Description

The 236A/E7 antibody reacts with human Foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3, a 49-55kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in ‘scurfy’ (sf) mice. Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

Intracellular staining and flow cytometric analysis of freshly isolated human peripheral blood mononuclear cells (PBMCs) with the 236A/E7 antibody using the Foxp3/Transcription Factor Staining Buffer Set (cat. 00-5523) and protocol reveals staining of the CD4+CD25bright population.

The epitope from 236A/E7 is different from that of PCH101 (cat. 72-5776). This antibody has also been shown to recognize rhesus macaque, sooty mangabey and cynomolgus macaque.
Description & Specifications

Specifications

Foxp3
Murine
Flow Cytometry (Intracellular Staining)
FITC
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test
236A/E7
Forkhead Box P3, Scurfin, JM2
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer