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Foxp3 Mouse anti-Human, Clone: 236A/E7, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $346.55

Specifications

Antigen Foxp3
Clone 236A/E7
Host Species Murine
Gene Alias Forkhead Box P3, Scurfin, JM2
Species Reactivity Human, Non-human primate, Rhesus Ma
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Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013068 Life Technologies
LS14477780
25μg Each for $158.05
501129542 Life Technologies
LS14477782
100μg Each for $346.55
Specifications

Description

The 236A/E7 antibody reacts with human Foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3, a 49-55kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in ‘scurfy’ (sf) mice. Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

Intracellular staining and flow cytometric analysis of freshly isolated human peripheral blood mononuclear cells (PBMCs) with the 236A/E7 antibody using the Foxp3/Transcription Factor Staining Buffer Set (cat. 00-5523) and protocol reveals staining of the CD4+CD25bright population.

The epitope from 236A/E7 is different from that of PCH101 (cat. 72-5776). This antibody has also been shown to recognize rhesus macaque, sooty mangabey and cynomolgus macaque.
Description & Specifications

Specifications

Foxp3
Murine
Human, Non-human primate, Rhesus Ma
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
236A/E7
Forkhead Box P3, Scurfin, JM2
Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL