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FOXJ1 Mouse anti-Human, Mouse, Clone: 2A5, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $332.05

Specifications

Antigen FOXJ1
Clone 2A5
Host Species Mouse
Gene Alias HFH-4, HFH4, Fox J1
Species Reactivity Human, Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013931

 
affymetrix
14996580
25μg Each for $143.55

501128960

 
affymetrix
14-9965-82
100μg Each for $332.05
Description & Specifications

Specifications

Antigen FOXJ1
Clone 2A5
Host Species Mouse
Gene Alias HFH-4, HFH4, Fox J1
Species Reactivity Human, Mouse
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 2A5 monoclonal antibody reacts with Foxj1, a 50kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.