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Alfa Aesar™ Fluocinolone acetonide

A glucocorticoid with anti-inflammatory properties

$75.57 - $411.74

Chemical Identifiers

CAS 67-73-2
Molecular Formula C24H30F2O6
Molecular Weight (g/mol) 452.495
MDL Number MFCD00010525
InChI Key FEBLZLNTKCEFIT-VSXGLTOVSA-N
Synonym fluocinolone acetonide, synalar, flucinar, synandone, fluonid, jellin, synamol, synemol, coriphate, fluovitif
PubChem CID 6215
ChEBI CHEBI:31623
SMILES CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ63996MC View Documents Alfa Aesar™
J63996MC
100mg Each for $75.57
 
AAJ6399603 View Documents Alfa Aesar™
J6399603
1g Each for $411.74
 
Description

Description

Applications
Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.

Solubility
Soluble in water (partly), DMSO, alcohol, chloroform and methanol.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Specifications

Chemical Identifiers

67-73-2
452.495
FEBLZLNTKCEFIT-VSXGLTOVSA-N
6215
CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C
C24H30F2O6
MFCD00010525
fluocinolone acetonide, synalar, flucinar, synandone, fluonid, jellin, synamol, synemol, coriphate, fluovitif
CHEBI:31623

Specifications

White
100mg
C24H30F2O6
14,4150
FEBLZLNTKCEFIT-VSXGLTOVSA-N
452.495
CHEBI:31623
Crystalline Powder
267°C to 269°C
67-73-2
MFCD00010525
fluocinolone acetonide, synalar, flucinar, synandone, fluonid, jellin, synamol, synemol, coriphate, fluovitif
CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C
6215
452.49
Fluocinolone acetonide
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : TU3830000