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Fibronectin Mouse anti-Human, Clone: FN-3, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $288.55

Specifications

Antigen Fibronectin
Clone FN-3
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245608

 
affymetrix
14986980
25μg Each for $129.05

50245609

 
affymetrix
14986982
100μg Each for $288.55
Description & Specifications

Specifications

Antigen Fibronectin
Clone FN-3
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.