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Thermo Scientific™ Lab Vision™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS231P1ABX

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Catalog No. MS231P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments with Thermo Scientific™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody.

Fibrillin-1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. fibrillin-1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in fibrillin-2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.

Host Species: Mouse

Clone: 11C1.3

Isotype: IgG1/κ

Species Reactivity: Human and Cow. Others not known.

Epitope: aa 451-909

Immunogen: Microfibrils from zonular apparatus of bovine eye

Molecular Weight: 350 kDa

Positive Control: Normal skin fibroblasts

Cellular Localization: Extracellular microfibrils

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen)
  • Western Blotting
  • Immunofluorescence
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Fibrillin-1 Ab-1
Monoclonal
1mg/mL
Bovine,Human
Murine
IgG2a kappa
RUO
Primary
Bovine,Human
Immunofluorescence,Immunohistochemistry (Frozen),Western Blotting
11C1.3
Unlabeled
Concentrated
Microfibrils from zonular apparatus of bovine eye
100μL
Extracellular Matrix
Monoclonal