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Thermo Scientific™ Lab Vision™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments.

Manufacturer: thermo scientific™ lab vision™  MS231P1ABX

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Catalog No. MS231P1ABX

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Description & Specifications

Specifications

Antigen Fibrillin-1 Ab-1
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Classification Monoclonal
Clone 11C1.3
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Microfibrils from zonular apparatus of bovine eye
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Extracellular Matrix
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments with Thermo Scientific™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody.

Fibrillin-1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. fibrillin-1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in fibrillin-2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.

Host Species: Mouse

Clone: 11C1.3

Isotype: IgG1/κ

Species Reactivity: Human and Cow. Others not known.

Epitope: aa 451-909

Immunogen: Microfibrils from zonular apparatus of bovine eye

Molecular Weight: 350 kDa

Positive Control: Normal skin fibroblasts

Cellular Localization: Extracellular microfibrils

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen)
  • Western Blotting
  • Immunofluorescence
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO