Thermo Scientific™ Lab Vision™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments.
Manufacturer: Thermo Scientific™ Lab Vision™ MS231P1ABX
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence and electron microscopy experiments with Thermo Scientific™ Fibrillin-1 Ab-1, Mouse Monoclonal Antibody.Fibrillin-1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. fibrillin-1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in fibrillin-2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
Host Species: Mouse
Species Reactivity: Human and Cow. Others not known.
Epitope: aa 451-909
Immunogen: Microfibrils from zonular apparatus of bovine eye
Molecular Weight: 350 kDa
Positive Control: Normal skin fibroblasts
Cellular Localization: Extracellular microfibrils
- Immunohistochemistry (Acetone-fixed frozen)
- Western Blotting
- Electron Microscopy
USA: RUO; Int'l: RUO
|Microfibrils from zonular apparatus of bovine eye|
|Immunofluorescence,Immunohistochemistry (Frozen),Western Blotting|