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FGFR3 Recombinant Human Protein DFS Item

FGFR3 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3145

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Catalog No. PV3145



Description

Description

FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.
Specifications

Specifications

NP_000133
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
49.8kDa
90% by SDS-PAGE
–80°C
1 Each
FGFR3, CEK2, JTK4
FGFR3 was pre-diluted in enzyme dilution buffer and assayed in 10mM HEPES (pH 7.5), 150mM NaCl, 10 MnCl2, 5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
FGF receptor
FGFR3 Recombinant Human Protein
Human
0.11mg/mL
2261
FGFR3 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Receptor tyrosine kinases
FGFR3 Recombinant Human Protein
Kinase assay
Baculovirus
Amino acids 399-806
680nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL
His Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.