FGFR1 [V561M] Recombinant Human Protein, Invitrogen™
FGFR1 (also known as FLT2) is part of the Fibroblast Growth Factor Receptor family of four membrane-spanning tyrosine kinases (FGFR1-4). Recombinant human FGFR1 (399-822; V561M) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Manufacturer: Life Technologies LSPV6344
FGFR1-4 serve as high-affinity receptors for 17 growth factors (FGF1-17). The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth. FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
|Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma|
|Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.|
|50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol|
|FLT2, CEK, FLG, KAL2, BFGFR, C-FGR, CD331, N-SAM|