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FGFR1 [V561M] Recombinant Human Protein, Invitrogen™ DFS Item

FGFR1 (also known as FLT2) is part of the Fibroblast Growth Factor Receptor family of four membrane-spanning tyrosine kinases (FGFR1-4). Recombinant human FGFR1 (399-822; V561M) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Manufacturer:  Life Technologies LSPV6343

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Catalog No. PV6343



Description

Description

FGFR1-4 serve as high-affinity receptors for 17 growth factors (FGF1-17). The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth. FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
74.0kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Kinase Assay
Human
GST Tag
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
10μg
FLT2, CEK, FLG, KAL2, BFGFR, C-FGR, CD331, N-SAM
aa 399-822
Yes
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