Thermo Scientific™ Lab Vision™ Factor XIII A Ab-2, Rabbit Polyclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Factor XIII A Ab-2, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB1464PABX
Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Factor XIII A Ab-2, Rabbit Polyclonal Antibody.Factor XIII A Ab-2 detects Factor XIII in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a Β-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimmer of M.W. 160 kDa. Factor XIII is present in plasma as an α2Β2 heterodimer (M.W. 320 kDa); whereas in platelets, only the α2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans.
Host Species: Rabbit
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII
Molecular Weight: 160 kDa (unreduced dimer); 80 kDa (reduced monomer)
Positive Control: Human recombinant Factor XIII A-subunit; Capillary hemangioma, dermatofibroma and placenta
Cellular Localization: Cytoplasmic and nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Factor XIII A Ab-2|
|Recombinant protein corresponding to A-subunit of coagulation Factor XIII|
|Ab without BSA/Azide (Frozen)|