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F4/80 Antigen Rat anti-Mouse, Clone: BM8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$433.55 - $709.05

Specifications

Antigen F4/80 Antigen
Clone BM8
Host Species Rat
Gene Alias Pan Macrophage Marker
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122959

 
affymetrix
16480185
500μg Each for $433.55

501122960

 
affymetrix
16480186
1mg Each for $709.05
Description & Specifications

Specifications

Antigen F4/80 Antigen
Clone BM8
Host Species Rat
Gene Alias Pan Macrophage Marker
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.