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F4/80 Antigen Rat anti-Mouse, Clone: BM8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$433.55 - $709.05

Specifications

Antigen F4/80 Antigen
Clone BM8
Host Species Rat
Gene Alias Pan Macrophage Marker
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122959 Life Technologies
LS16480185
500μg Each for $433.55
501122960 Life Technologies
LS16480186
1mg Each for $709.05
Specifications

Description

The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.
Description & Specifications

Specifications

F4/80 Antigen
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, no sodium azide
BM8
Pan Macrophage Marker
Flow Cytometry
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL