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F4/80 Antigen Rat anti-Mouse, Biotin, Clone: BM8, eBioscience™

Rat Monoclonal Antibody

$172.55 - $462.55

Specifications

Antigen F4/80 Antigen
Clone BM8
Host Species Rat
Gene Alias EMR1, Ly71, Pan Macrophage Marker
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011872 Life Technologies
LS13480181
50μg Each for $172.55
501128907 Life Technologies
LS13480182
100μg Each for $288.55
501128940 Life Technologies
LS13480185
500μg Each for $462.55
Specifications

Description

The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 160kDa surface receptor. It belongs to the EGF-TM7 family of proteins. As such it contains seven EGF-like domains on its extracellular N-terminus, seven transmembrane spanning sequences, and an intracellular C-terminal domain showing homology to other TM7 superfamily members. The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as well. Expression of F4/80 commences during early myeloid development in vivo and can be upregulated on BM cells stimulated in vitro with M-CSF. Some populations of macrophages, especially in the lymphoid microenvironment, may be devoid of F4/80.
Description & Specifications

Specifications

F4/80 Antigen
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
BM8
EMR1, Ly71, Pan Macrophage Marker
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL