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Thermo Scientific™ EZ-Link™ NHS-PEG12-Biotin

Biotinylate protein amines and maximize solubility of proteins with this very long (56.0A) NHS-ester biotinylation reagent containing a pegylated, water-soluble spacer arm.

Manufacturer: thermo scientific™  21312**

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Catalog No. PI21312

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Description & Specifications


Sufficient For Approx. 12 uses to label a total of 177mg of IgG using typical conditions
Description EZ-Link NHS-PEG12-Biotin
Formulation NHS ester of biotin with a 12-unit ethyleneglycol spacer
Chemical Reactivity Amine
PEGylated Yes
Quantity 25mg
Membrane Permeable No
Spacer Arm Length 56
Molecular Weight 941.09
Water Soluble Yes
Cleavable No

Thermo Scientific™ EZ-Link NHS-PEG12-Biotin is very long, pegylated biotinylation reagent for simple and efficient biotin labeling of antibodies, proteins and other primary amine-containing macromolecules.


  • Water-soluble polyethylene glycol (PEG) spacer arm increases solubility of labeled protein
  • Excellent purity, molecular weight uniformity and amine-reactivity
  • Long spacer arm reduces steric hindrance when binding to avidin molecules