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Alfa Aesar™ Etoposide

Topoisomerase inhibitor and inducer of apoptosis

$80.50 - $200.47

Chemical Identifiers

CAS 33419-42-0
Molecular Formula C29H32O13
Molecular Weight (g/mol) 588.562
MDL Number MFCD00869325
InChI Key VJJPUSNTGOMMGY-NZLMILQCSA-N
Synonym vjjpusntgommgy-nzlmilqcsa
PubChem CID 50936917
IUPAC Name (9R)-5-[[(2R,6R,7R,8R)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
SMILES CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ63651MB View Documents Alfa Aesar™
J63651MB
25mg Each for $80.50
 
AAJ63651MC View Documents Alfa Aesar™
J63651MC
100mg Each for $200.47
 
Description

Description

Applications
Etoposide is used as a inhibits DNA synthesis and is very active against cells in the late S and G2 phases of the cell cycle. Etoposide was reported to be used to serum starve Saos-2 M5(p53-/-) cells which were transfected by electroporation with indicated expression plasmids for flag-E2F1 and myc-EBNA3C for selection of colony forming units, thus studying the blocking effect of EBV Nuclear Antigen 3C on E2F1 Mediated Apoptosis Induced by the DNA Damage Response.

Solubility
Insoluble in water.

Notes
Store solutions in DMSO at 4°C. For long term storage prepare aliquots and store at -20°C.
Specifications

Chemical Identifiers

33419-42-0
588.562
VJJPUSNTGOMMGY-NZLMILQCSA-N
50936917
CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
C29H32O13
MFCD00869325
vjjpusntgommgy-nzlmilqcsa
(9R)-5-[[(2R,6R,7R,8R)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one

Specifications

−107° (c=1 in Methanol/Dichloromethane 1:9)
236°C to 251°C
33419-42-0
MFCD00869325
vjjpusntgommgy-nzlmilqcsa
CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
588.562
588.56
Etoposide
White
25mg
C29H32O13
14,3886
VJJPUSNTGOMMGY-NZLMILQCSA-N
(9R)-5-[[(2R,6R,7R,8R)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
50936917
Powder
Safety and Handling

Safety and Handling

GHS H Statement
H350-H302
May cause cancer.
Harmful if swallowed.

GHS P Statement
P281-P264-P301+P312-P308+P313-P405-P501a
Use personal protective equipment as required.
Wash thoroughly after handling.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Danger

RTECSNumber : KC0190000