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Ethyl isonipecotate, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals B2060122
Description
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIt is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
Solubility
Fully miscible with water.
Notes
Store at room temperature. Incompatible with strong oxidizing agents.
Specifications
Ethyl isonipecotate | |
1.021 | |
80°C (176°F) | |
1.46 | |
100 g | |
ethyl 4-piperidinecarboxylate, ethyl isonipecotate, piperidine-4-carboxylic acid ethyl ester, ethylpiperidine-4-carboxylate, 4-piperidinecarboxylic acid, ethyl ester, isonipecotic acid ethyl ester, 4-piperidinecarboxylic acid ethyl ester, 4-carbethoxypiperidine, 4-carboethoxypiperidine, 4-ethoxycarbonyl piperidine | |
RUJPPJYDHHAEEK-UHFFFAOYSA-N | |
ethyl piperidine-4-carboxylate | |
70770 | |
98% |
1126-09-6 | |
203°C to 205°C | |
C8H15NO2 | |
MFCD00006003 | |
118419 | |
Fully miscible with water. | |
CCOC(=O)C1CCNCC1 | |
157.21 | |
157.21 |
Chemical Identifiers
1126-09-6 | |
157.21 | |
RUJPPJYDHHAEEK-UHFFFAOYSA-N | |
70770 | |
CCOC(=O)C1CCNCC1 |
C8H15NO2 | |
MFCD00006003 | |
ethyl 4-piperidinecarboxylate, ethyl isonipecotate, piperidine-4-carboxylic acid ethyl ester, ethylpiperidine-4-carboxylate, 4-piperidinecarboxylic acid, ethyl ester, isonipecotic acid ethyl ester, 4-piperidinecarboxylic acid ethyl ester, 4-carbethoxypiperidine, 4-carboethoxypiperidine, 4-ethoxycarbonyl piperidine | |
ethyl piperidine-4-carboxylate |
Safety and Handling
GHS H Statement
H315-H319-H335-H227
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Combustible liquid.
P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
H227-H315-H319-H335
EINECSNumber : 214-416-7
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only