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Ethyl 5-methylindole-2-carboxylate, 98%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L1714603
Description
Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions, reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists, reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents, reactant for Friedel-Crafts acylation with nitrobenzoyl chloride. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.
Reactant for oximation reactionsThis Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsReactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions, reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists, reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents, reactant for Friedel-Crafts acylation with nitrobenzoyl chloride. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine. · Reactant for oximation reactions
Solubility
Soluble in methanol, and dichloromethane. Insoluble in water.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Specifications
Ethyl 5-methylindole-2-carboxylate | |
161°C to 165°C | |
C12H13NO2 | |
1 g | |
ethyl 5-methylindole-2-carboxylate, 2-carbethoxy-5-methylindole, 5-methylindole-2-carboxylic acid ethyl ester, 5-methyl-1h-indole-2-carboxylic acid ethyl ester, pubchem7940, acmc-1brcs, 5-methyl-2-ethoxycarbonyl indole, ethyl 5-methyl-2-indolecarboxylate, 5-methyl-1h-indole-2-carboxylic acid, ethyl ester | |
KMVFKXFOPNKHEM-UHFFFAOYSA-N | |
ethyl 5-methyl-1H-indole-2-carboxylate | |
232919 | |
99% |
16382-15-3 | |
236°C (4 mmHg) | |
MFCD00022703 | |
159437 | |
Soluble in methanol,and dichloromethane. Insoluble in water. | |
CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C | |
203.241 | |
203.24 |
Chemical Identifiers
16382-15-3 | |
203.241 | |
KMVFKXFOPNKHEM-UHFFFAOYSA-N | |
232919 | |
CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C |
C12H13NO2 | |
MFCD00022703 | |
ethyl 5-methylindole-2-carboxylate, 2-carbethoxy-5-methylindole, 5-methylindole-2-carboxylic acid ethyl ester, 5-methyl-1h-indole-2-carboxylic acid ethyl ester, pubchem7940, acmc-1brcs, 5-methyl-2-ethoxycarbonyl indole, ethyl 5-methyl-2-indolecarboxylate, 5-methyl-1h-indole-2-carboxylic acid, ethyl ester | |
ethyl 5-methyl-1H-indole-2-carboxylate |
Safety and Handling
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only