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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-21, Rat Monoclonal Antibody


Ensure accurate, reproducible results in western blotting and ELISA experiments with Thermo Scientific™ Estrogen Receptor Ab-21, Rat Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RT1641P

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Catalog No. RT1641P

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Description & Specifications

Specifications

Format Concentrated
Cross Reactivity Human
Antigen Estrogen Receptor Ab-21
Host Species Rat
Immunogen Estrogen receptor purified from MCF-7 cells
Applications Western Blotting
Quantity 1mL
Isotype IgG1 kappa
Regulatory Status RUO
Clone H222
Classification Monoclonal
Research Discipline Oncogenesis
Type Primary
Concentration 200µg/mL
Conjugate Unlabeled

Ensure accurate, reproducible results in western blotting and ELISA experiments with Thermo Scientific™ Estrogen Receptor Ab-21, Rat Monoclonal Antibody.

ER protein exhibits six functionally discrete domains required for transcription activation, binding to estrogen response element (ERE), constitutive dimerization, binding to heat shock proteins, and ligand recognition. It is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors may improve response to anti-estrogen therapy.

Host Species: Rat

Clone: H222

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Shows broad species reactivity.

Immunogen: Estrogen receptor purified from MCF-7 cells

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • ELISA

Note:

USA: RUO; Int'l: RUO