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Estrogen Receptor Ab-17 Rabbit Polyclonal Antibody, Epredia™
Epredia™ Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody provides accurate, reproducible results.
Supplier: Thermo Fisher Scientific RB1521P0
Description
ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Rat, Mouse, Rabbit, Sheep, Pig and Cow. Others not known.
Epitope: N-terminal
Immunogen: A synthetic peptide from the N-terminus of human estrogen receptor, α protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
| Estrogen Receptor Ab-17 | |
| Polyclonal | |
| Unconjugated | |
| A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein | |
| 100 μL | |
| Steroids Hormones and Growth Factors | |
| Bovine, Human, Mouse, Porcine, Rabbit, Rat | |
| IgG |
| Immunoprecipitation, Western Blot | |
| 1mg/mL | |
| Rabbit | |
| Purified with BSA and azide | |
| RUO | |
| Primary | |
| Concentrated |