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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  RB1521PABX

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Catalog No. RB1521PABX

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Description & Specifications

Specifications

Antigen Estrogen Receptor Ab-17
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody.

ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Rat, Mouse, Rabbit, Sheep, Pig and Cow. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminus of human estrogen receptor, α protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO