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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS168P1ABX

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Catalog No. MS168P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: AER314

Isotype: IgG1/λ

Species Reactivity: Human, Cow, Rabbit, Mouse and Rat. Others not known.

Epitope: aa 125-165

Immunogen: Purified, SDS-denatured calf uterus estrogen receptor (ER)

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Affinity Purification
  • Gel Supershift
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Estrogen Receptor Ab-1
Monoclonal
1mg/mL
Bovine,Human,Mouse,Rabbit,Rat
Murine
IgG1 lambda
RUO
Primary
Bovine,Human,Murine,Rabbit,Rat
Immunoprecipitation
AER314
Unlabeled
Concentrated
Purified, SDS-denatured calf uterus estrogen receptor (ER)
100μL
Steroids Hormones and Growth Factors
Monoclonal