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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS168P1ABX

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Catalog No. MS168P1ABX

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Description & Specifications

Specifications

Clone AER314
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rabbit
Cross Reactivity Rat
Antigen Estrogen Receptor Ab-1
Isotype IgG1 lambda
Host Species Mouse
Regulatory Status RUO
Quantity 100µL
Immunogen Purified, SDS-denatured calf uterus estrogen receptor (ER)
Format Concentrated
Applications Immunoprecipitation
Conjugate Unlabeled
Type Primary
Concentration 1mg/mL
Classification Monoclonal
Research Discipline Steroids Hormones and Growth Factors

Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: AER314

Isotype: IgG1/λ

Species Reactivity: Human, Cow, Rabbit, Mouse and Rat. Others not known.

Epitope: aa 125-165

Immunogen: Purified, SDS-denatured calf uterus estrogen receptor (ER)

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Affinity Purification
  • Gel Supershift
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO