Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS168P1ABX

 View more versions of this product

Catalog No. MS168P1ABX

  • / Each
 

Description & Specifications

Specifications

Clone AER314
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rabbit
Cross Reactivity Rat
Antigen Estrogen Receptor Ab-1
Host Species Mouse
Isotype IgG1 lambda
Regulatory Status RUO
Quantity 100µL
Format Concentrated
Applications Immunoprecipitation
Immunogen Purified, SDS-denatured calf uterus estrogen receptor (ER)
Research Discipline Steroids Hormones and Growth Factors
Type Primary
Classification Monoclonal
Concentration 1mg/mL
Conjugate Unlabeled

Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: AER314

Isotype: IgG1/λ

Species Reactivity: Human, Cow, Rabbit, Mouse and Rat. Others not known.

Epitope: aa 125-165

Immunogen: Purified, SDS-denatured calf uterus estrogen receptor (ER)

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Affinity Purification
  • Gel Supershift
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO