Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments.
Manufacturer: Thermo Scientific™ Lab Vision™ MS168P1ABX
Ensure accurate, reproducible results in affinity purification, gel supershift and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-1, Mouse Monoclonal Antibody.The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Host Species: Mouse
Species Reactivity: Human, Cow, Rabbit, Mouse and Rat. Others not known.
Epitope: aa 125-165
Immunogen: Purified, SDS-denatured calf uterus estrogen receptor (ER)
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells
Cellular Localization: Nuclear
- Affinity Purification
- Gel Supershift
- Immunoprecipitation (Native and denatured)
USA: RUO; Int'l: RUO
|Estrogen Receptor Ab-1|
|Purified, SDS-denatured calf uterus estrogen receptor (ER)|
|Steroids Hormones and Growth Factors|