Thermo Scientific™ Lab Vision™ ERCC1 Ab-2, Mouse Monoclonal Antibody
Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS671P1ABX
Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-2, Mouse Monoclonal Antibody.The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Elevated levels of ERCC1 have also been reported in Cisplatin-resistant cells.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant full-length human ERCC1 protein
Molecular Weight: 33-36 kDa
Cellular Localization: Nuclear
- Western Blotting
USA: RUO; Int'l: RUO
|Recombinant full length human ERCC1 protein|