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Thermo Scientific™ Lab Vision™ ERCC1 Ab-2, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-2, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS671P1ABX

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Catalog No. MS671P1ABX


 

Specifications

Description

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-2, Mouse Monoclonal Antibody.

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Elevated levels of ERCC1 have also been reported in Cisplatin-resistant cells.

Host Species: Mouse

Clone: 8F1

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant full-length human ERCC1 protein

Molecular Weight: 33-36 kDa

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

ERCC1 Ab-2
Monoclonal
1mg/mL
Concentrated
Recombinant full length human ERCC1 protein
100μL
DNA Repair
Monoclonal
Immunoprecipitation,Western Blotting
8F1
Unlabeled
Murine
IgG2b
RUO
Primary
Human,Rat