Thermo Scientific™ Lab Vision™ ERCC1 Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS647P1ABX
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-1, Mouse Monoclonal Antibody.The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Elevated levels of ERCC1 have also been reported in Cisplatin-resistant cells.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Full-length recombinant human ERCC1 protein
Molecular Weight: 33-36 kDa
Positive Control: A431 or HeLa cells
Cellular Localization: Nuclear
- Immunohistochemistry (Not suitable)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|Full length recombinant human ERCC1 protein|