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Thermo Scientific™ Lab Vision™ ERCC1 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS647P1ABX

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Catalog No. MS647P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ ERCC1 Ab-1, Mouse Monoclonal Antibody.

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Elevated levels of ERCC1 have also been reported in Cisplatin-resistant cells.

Host Species: Mouse

Clone: 3H11

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Full-length recombinant human ERCC1 protein

Molecular Weight: 33-36 kDa

Positive Control: A431 or HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

ERCC1 Ab-1
Monoclonal
1mg/mL
Human
Murine
IgG2a kappa
RUO
Primary
Human
Immunoprecipitation
3H11
Unlabeled
Concentrated
Full length recombinant human ERCC1 protein
100μL
DNA Repair
Monoclonal