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ErbB4 (HER4) DFS Item

ErbB4 (HER4)

Manufacturer:  Life Technologies LSPV3626

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Catalog No. PV3626



Description

Description

Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3. ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.
Specifications

Specifications

NP_005226
Oncology and genetic disease research, pharma and biopharma, protein assays and analysis, target and lead identification and validation
61.6kDa
85% by SDS-PAGE
–80°C
1 Each
ErbB4 (HER4)
ERBB4 was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10 MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
EGF receptor (ErbB)
ErbB4 (HER4)
Human
0.34mg/mL
2066
ERBB4 (HER4)
10μg
For research use only. Not for use in diagnostic procedures
Receptor tyrosine kinases
ErbB4 (HER4)
Kinase assay
Baculovirus
Amino acids 708-993
550nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.