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ErbB2 (HER2) DFS Item

ErbB2 (HER2)

Manufacturer:  Life Technologies LSPV3590

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Catalog No. PV3590



Description

Description

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
Specifications

Specifications

NP_004439
Protein assays and analysis
Frozen
ERBB2 (HER2)
1mg
For research use only. Not for use in diagnostic procedures
ErbB2 (HER2), NEU
ERBB2 (HER2) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 5 MnCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% CHAPS, 200μM ATP, 1000μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Baculovirus
Amino acids 676-1255
78nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
His Tag
0.33mg/mL
Frozen
68.6kDa
60% by SDS-PAGE
–80°C
1 Each
ErbB2 (HER2)
Kinase assay
EGF receptor (ErbB)
ErbB2 (HER2)
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.