Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-3, Mouse Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence, immunoprecipitation and flow cytometry experiments.
Manufacturer: Thermo Scientific™ Lab Vision™ MS311P1ABX
Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-3, Mouse Monoclonal Antibody.EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Host Species: Mouse
Species Reactivity: Human and Horse. Does not react with mouse. Others not known.
Epitope: aa 6-273
Immunogen: A431 human epidermoid cells
Molecular Weight: 170 kDa (wild type)
Positive Control: A431 cells express only the intact and not the vIII variant of EGFR. HC2 20 d2 cells express the vIII variant. In normal breast, ducts and lobules show diffuse cytoplasmic staining.
Cellular Localization: Membrane
- Immunohistochemistry (Frozen only)
- Western Blotting (Not suitable)
- Immunoprecipitation (Native only)
- Flow Cytometry
USA: RUO; Int'l: RUO
|Epidermal Growth Factor Receptor/EGFR Ab-3|
|A431 human epidermoid cells|