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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS609P1ABX

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Catalog No. MS609P1ABX

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Description & Specifications

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-13
Applications Immunoprecipitation
Classification Monoclonal
Clone 528 + 199.12
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12)
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary

Obtain accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 528 + 199.12

Isotype: IgG2a + IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12)

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO