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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS609P1ABX

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Catalog No. MS609P1ABX

  • / Each
 

Description & Specifications

Specifications

Quantity 100µL
Host Species Mouse
Antigen Epidermal Growth Factor Receptor/EGFR Ab-13
Clone 528 + 199.12
Regulatory Status RUO
Immunogen Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12)
Cross Reactivity Human
Applications Immunoprecipitation
Format Concentrated
Isotype IgG2a
Classification Monoclonal
Research Discipline EGFR Family
Type Primary
Conjugate Unlabeled
Concentration 1mg/mL

Obtain accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-13, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 528 + 199.12

Isotype: IgG2a + IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Partially purified EGFR from A431 cells (clone 528) and extracellular domain of recombinant human EGFR protein (clone 199.12)

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO