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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody


Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS400P1ABX

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Catalog No. MS400P1ABX

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Description & Specifications

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48)
Host Species Mouse
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Cross Reactivity Human
Isotype IgG1 IgG2a
Quantity 100µL
Format Concentrated
Immunogen Extracellular and cytoplasmic domains of recombinant human EGFR protein
Clone 111.6+199.12+ F4+11E8
Research Discipline EGFR Family
Type Primary
Classification Monoclonal
Conjugate Unlabeled
Concentration 1mg/mL

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6 + 199.12 + F4 + 11E8

Isotype: IgG1 + IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Extracellular and cytoplasmic domain

Immunogen: Extracellular and cytoplasmic domains of recombinant human EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native only)

Note:

USA: RUO; Int'l: RUO