Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody


Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS400P1ABX

 View more versions of this product

Catalog No. MS400P1ABX

  • / Each
 

Description & Specifications

Specifications

Regulatory Status RUO
Antigen Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48)
Applications Immunoprecipitation
Applications Western Blotting
Cross Reactivity Human
Host Species Mouse
Quantity 100µL
Isotype IgG1 IgG2a
Format Concentrated
Immunogen Extracellular and cytoplasmic domains of recombinant human EGFR protein
Clone 111.6+199.12+ F4+11E8
Conjugate Unlabeled
Type Primary
Classification Monoclonal
Research Discipline EGFR Family
Concentration 1mg/mL

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6 + 199.12 + F4 + 11E8

Isotype: IgG1 + IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Extracellular and cytoplasmic domain

Immunogen: Extracellular and cytoplasmic domains of recombinant human EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native only)

Note:

USA: RUO; Int'l: RUO