Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments.
Manufacturer: Thermo Scientific™ Lab Vision™ MS400P1ABX
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48), Mouse Monoclonal Antibody.EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Host Species: Mouse
Clone: 111.6 + 199.12 + F4 + 11E8
Isotype: IgG1 + IgG2a
Species Reactivity: Human. Does not react with mouse and rat. Others not known.
Epitope: Extracellular and cytoplasmic domain
Immunogen: Extracellular and cytoplasmic domains of recombinant human EGFR protein
Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)
Positive Control: A431 cells
Cellular Localization: Membrane
- Western Blotting
- Immunoprecipitation (Native only)
USA: RUO; Int'l: RUO
|Epidermal Growth Factor Receptor/EGFR Ab-12 (Cocktail R19/48)|
|Extracellular and cytoplasmic domains of recombinant human EGFR protein|