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Epidermal Growth Factor Receptor/EGFR Ab-11 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.
Supplier: Thermo Fisher Scientific MS396P1ABX
Description
EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Host Species: Mouse
Clone: 199.12
Isotype: IgG2a
Species Reactivity: Human. Others not known.
Epitope: Extracellular domain
Immunogen: Extracellular domain of human recombinant EGFR protein
Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)
Positive Control: A431 cells
Cellular Localization: Membrane
Recommended for:
- Western Blotting
- Immunoprecipitation (Native only)
- Effect on EGF Binding (Noninhibitory)
Note:
USA: RUO; Int'l: RUO
Specifications
| Epidermal Growth Factor Receptor/EGFR Ab-11 | |
| 199.12 | |
| Unconjugated | |
| Extracellular domain of human recombinant EGFR protein | |
| RUO | |
| Primary | |
| Concentrated |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| EGFR Family | |
| Human | |
| IgG2a |