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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-11, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  MS396P1ABX

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Catalog No. MS396P1ABX

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Description & Specifications

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-11
Classification Monoclonal
Clone 199.12
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Extracellular domain of human recombinant EGFR protein
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-11, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 199.12

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Noninhibitory)

Note:

USA: RUO; Int'l: RUO