Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments.

$272.86 - $1,437.80

Specifications

Antigen Epidermal Growth Factor Receptor /EGFR Ab-1
Clone 528
Applications Flow Cytometry
Applications Immunoprecipitation
Applications Flow Cytometry
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS268B

 
thermo scientific™ lab vision™
MS-268-B
200�g/mL Biotin 1mL Each for $1,437.80

MS268B0

 
thermo scientific™ lab vision™
MS-268-B0
200�g/mL Biotin 100µL Each for $365.14

MS268B1

 
thermo scientific™ lab vision™
MS-268-B1
200�g/mL Biotin 500µL Each for $908.76

MS268P

 
thermo scientific™ lab vision™
MS-268-P
200�g/mL Unlabeled 1mL Each for $1,104.67

MS268P0

 
thermo scientific™ lab vision™
MS-268-P0
200�g/mL Unlabeled 100µL Each for $272.86

MS268P1

 
thermo scientific™ lab vision™
MS-268-P1
200�g/mL Unlabeled 500µL Each for $699.39

MS268P1ABX

 
thermo scientific™ lab vision™
MS268P1ABX
1mg/mL Unlabeled 100µL Each for $771.76

MS268PABX

 
thermo scientific™ lab vision™
MS-268-PABX
1mg/mL Unlabeled 200µL Each for $1,177.29
Description & Specifications

Specifications

Antigen Epidermal Growth Factor Receptor /EGFR Ab-1
Clone 528
Applications Flow Cytometry
Applications Immunoprecipitation
Applications Flow Cytometry
Applications Immunoprecipitation
Classification Monoclonal
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Canine
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary
Immunogen Purified EGFR from A431 cells
Isotype IgG2a

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 528

Isotype: IgG2a

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Purified EGFR from A431 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Affinity Purification
  • Blocks EGF/TGFα-induced Activation of EGFR
  • Inhibits Binding of EGFR Ab-2 (clone 225) to EGFR
  • Inhibits Proliferation of A431 Cells
  • Arrests Tumor Growth in vivo
  • Immunoprecipitation (Native only)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO