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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments.

$293.41 - $1,545.90

Specifications

Antigen Epidermal Growth Factor Receptor /EGFR Ab-1
Clone 528
Applications Flow Cytometry,Immunoprecipitation,Flow Cytometry,Immunoprecipitation
Classification Monoclonal
Format Concentrated
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
MS268B Thermo Scientific™ Lab Vision™
MS268B
200μg/mL Biotin 1mL Each for $1,545.90
MS268B0 Thermo Scientific™ Lab Vision™
MS268B0
200μg/mL Biotin 100μL Each for $392.78
MS268B1 Thermo Scientific™ Lab Vision™
MS268B1
200μg/mL Biotin 500μL Each for $977.08
MS268P Thermo Scientific™ Lab Vision™
MS268P
200μg/mL Unlabeled 1mL Each for $1,187.84
MS268P0 Thermo Scientific™ Lab Vision™
MS268P0
200μg/mL Unlabeled 100μL Each for $293.41
MS268P1 Thermo Scientific™ Lab Vision™
MS268P1
200μg/mL Unlabeled 500μL Each for $751.98
MS268P1ABX Thermo Scientific™ Lab Vision™
MS268P1ABX
1mg/mL Unlabeled 100μL Each for $829.82
MS268PABX Thermo Scientific™ Lab Vision™
MS268PABX
1mg/mL Unlabeled 200μL Each for $1,265.90
Specifications

Description

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 528

Isotype: IgG2a

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Purified EGFR from A431 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Affinity Purification
  • Blocks EGF/TGFα-induced Activation of EGFR
  • Inhibits Binding of EGFR Ab-2 (clone 225) to EGFR
  • Inhibits Proliferation of A431 Cells
  • Arrests Tumor Growth in vivo
  • Immunoprecipitation (Native only)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Epidermal Growth Factor Receptor /EGFR Ab-1
Flow Cytometry,Immunoprecipitation,Flow Cytometry,Immunoprecipitation
Concentrated
RUO
Primary
IgG2a
528
Monoclonal
Murine
EGFR Family
Purified EGFR from A431 cells