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Thermo Scientific™ Lab Vision™ Emerin Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry applications with Thermo Scientific™ Emerin Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1751S

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Catalog No. MS1751S

  • / Each
 

Description & Specifications

Specifications

Antigen Emerin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 4G5
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Recombinant protein corresponding to 222 amino acid fragment near N-terminus of human emerin protein
Isotype IgG1
Purification Method Tonsil
Quantity 1mL
Regulatory Status RUO
Research Discipline Muscle Biology
Type Primary

Ensure accurate, reproducible results in immunohistochemistry applications with Thermo Scientific™ Emerin Ab-1, Mouse Monoclonal Antibody.

Emerin is a serine-rich, ubiquitously expressed protein with the highest concentration in skeletal and cardiac muscles. It is localized in the nuclear membrane and is coded by the STA gene at the  Xq28 locus. Emerin deficiency is the main causal feature of Emery-Dreifuss muscular dystrophy (EDMD), which is an X-linked disorder leading to weakening of muscles and cardiomyopathy presented as heart block.

Host Species: Mouse

Clone: 4G5

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Near N-terminus

Immunogen: Recombinant protein corresponding to 222 amino acid fragment near N-terminus of human emerin protein

Molecular Weight: 34 kDa

Positive Control: Tonsil

Cellular Localization: Perinuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO