missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

EIF2AK3 (PERK) Recombinant Human Protein DFS Item

EIF2AK3 (PERK) Recombinant Human Protein

Manufacturer:  Life Technologies LSPV5106

 View more versions of this product

Catalog No. PV5106



Description

Description

EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Specifications

Specifications

NP_004827.3
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
93.6kDa
60% by SDS-PAGE
–80°C
1 Each
NP_004827.3
EIF2AK3 (PERK) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β−glycerophosphate, 2mM DTT, 0.02% Triton™ X-100, 200μM ATP, 267μg/mL RS domain derived peptide substrate (GRSRSRSRSR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
PEK kinase family
EIF2AK3 (PERK) Recombinant Human Protein
Human
0.12mg/mL
9451
EIF2AK3 (PERK) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
EIF2AK3 (PERK) Recombinant Human Protein
Kinase assay
Baculovirus
aa 536 to 1116
22nmoles of phosphate transferred to RS domain derived peptide substrate (GRSRSRSRSR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 4.17μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.