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EIF2AK2 (PKR) Recombinant Human Protein DFS Item

EIF2AK2 (PKR) Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4821

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Catalog No. PV4821



Description

Description

EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
Specifications

Specifications

NP_002750.1
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
62.2kDa
75% by SDS-PAGE
–80°C
1 Each
EIF2AK2 (PKR)
EIF2AK2 (PKR) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β−glycerophosphate, 2mM DTT, 0.02% Triton™ X-100, 200μM ATP, 267μg/mL RS domain derived peptide substrate (GRSRSRSRSR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
PEK kinase family
EIF2AK2 (PKR) Recombinant Human Protein
Human
0.13mg/mL
9833
EIF2AK2 (PKR) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
EIF2AK2 (PKR) Recombinant Human Protein
Kinase assay
Baculovirus
aa 252 to 551
2170nmoles of phosphate transferred to RS domain derived peptide substrate (GRSRSRSRSR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 0.167μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.