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EIF2AK1 (HRI) Human Protein DFS Item

EIF2AK1 (HRI) Human Protein

Manufacturer:  Life Technologies LSPV5856

Catalog No. PV5856



Description

Description

EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
Specifications

Specifications

NP_055228.2
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
Frozen
98.6kDa
60% by SDS-PAGE
–80°C
1 Each
EIF2AK1 (HRI)
EIF2AK1 (HRI) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.02% Triton™ X-100, 100μM ATP, 266μg/mL RS domain derived peptide substrate (GRSRSRSRSR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
PEK
4nmoles of phosphate transferred to RS domain derived peptide substrate (GRSRSRSRSR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 3.33μg/mL
GST Tag
0.34mg/mL
Frozen
EIF2AK1
EIF2AK1 (HRI) Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
EIF2AK1 (HRI) Human Protein
Kinase assay
Baculovirus
EIF2AK1 (HRI) Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.