EGFR (ErbB1) [L861Q] Recombinant Human Protein, Invitrogen™
The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
Manufacturer: Life Technologies LSPV4191
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.
|Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.|
|EGF Receptor (ErbB) Kinase Family|
|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|
|50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol|
|RUO - research use only|
|EGFR (ErbB1) L861Q|