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Alfa Aesar™ E-64

Selective and irreversible cysteine protease inhibitor

$617.26 - $617.26

Chemical Identifiers

CAS 66701-25-5
Molecular Formula C15H27N5O5
Formula Weight 357.4
MDL Number MFCD00080261
Beilstein 1405664
Synonym trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane
Chemical Name or Material E-64
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ62933LB0 SDS Alfa Aesar™
J62933LB0
5mg N/A N/A  
Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
AAJ62933MB SDS Alfa Aesar™
J62933MB
25mg Each for $617.26
Specifications

Description

Applications
It is used as a broad spectrum cysteine proteinase and calpain activation inhibitor. Additionally, Prevotella intermediate studies report that E-64 blocks the breakdown of methaemoglobin and the oxidation of oxyhaemoglobin by InpA. E-64 has also been used to study excystation in Giardia lamblia. E-64 is an inhibitor of Calpain, cathepsin K and cathepsin S. E-64 is an effective ligand for affinity purification of cysteine proteases. When coupled to a thiolated affinity matrix, binding is no longer irreversible, but specificity is retained

Solubility
Soluble in DMSO (25mg/ml), or water (20mg/ml)

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong acids, strong bases.
Description & Specifications

Chemical Identifiers

66701-25-5
357.4
1405664
E-64
C15H27N5O5
MFCD00080261
trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane

Specifications

66701-25-5
C15H27N5O5
MFCD00080261
trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane
White to Off-white
+24° (c=1 in 1N HCl)
E-64
Powder
357.4
1405664
Soluble in DMSO (25mg/ml), or water (20mg/ml)
5mg
Light Sensitive

Safety and Handling

RTECSNumber : RR0390000

Recommended Storage : −30° to −10°C